Oferta specjalna nr W24 Ceny specjalne na wydawnictwa dotyczące onkologii Oferowane pozycje: Oncology. An Evidence-Based Approach Hyperthermia In Cancer Treatment. A Primer New Trends in Cancer for the 21st Century Breast Cancer Management and Molecular Medicine: Towards Tailored Approaches Breast Cancer, Third Edition Prognostic Factors in Cancer, 3rd Edition Infections Causing Human Cancer Oncology An Evidence-Based Approach Chang, A.E.; Ganz, P.A.; Hayes, D.F.; Kinsella, T.; Pass, H.I.; Schiller, J.H.; Stone, R.M.; Strecher, V. (Eds.) 2006, XLII, 2022 p., 200 illus., Hardcover ISBN: 0-387-24291-0 Price: 199,95 EUR + shipping 10,00 EUR NASZA CENA: 760,00 PLN* About this book Oncology: An Evidence-Based Approach is a textbook designed to reflect the principles and current practice of oncology with contributors from the fields of medical, surgical, and radiation oncology. The textbook will incorporate an evidence-based approach, enabling the reader to make decisions on the basis of concrete data. Sections on solid tumors, hematologic malignancies and the practice of oncology address the natural history and therapy for the full spectrum of neoplastic diseases in the adult. Further sections present fundamentals of supportive care of the cancer patient, the management of oncologic emergencies and acute toxicities of therapy, as well as care of metastatic disease and the terminally-ill patient. Breaking new ground, the textbook features thoughtful, in-depth sections on cancer prevention and control, cancer surviorship, the economics of cancer care, and cancer informatics. Cancer imaging is covered with an organ system-based approach, with an additional chapter on the especially intriguing potential of PET. Furthermore, a comprehensive section on translational basic science reviews the fundamentals of molecular biology, the cell cycle and signal transduction, carcinogenesis, cancer genetics, the biology of invations and metastasis, and tumor immunology. Table of contents Section I. Principles of Oncology * Evidence-Based Approach to Oncology * Principles of Chemotherapy * Principles of Radiation Oncology * Principles of Surgical Therapy in Oncology * Principles of Targeted and Biological Therapies * Biologic Principles of Hematopoietic Stem Cell Transplantation * Evaluation of Tumor Markers: An Evidence-Based Guide for Determination of Clinical Utility * Design and Analysis of Oncology Clinical Trials * Ethics of Clinical Oncology Research * Informatics Infrastructure for Evidence-Based Cancer Medicine * Economics of Cancer Care * Principles of Screening for Cancer * Patient Decision Making * Establishing an Interdisciplinary Oncology Team * Principles of Complementary and Alternative Medicine for Cancer * Section II. Translational Basic Science * Fundamental Aspects of the Cell Cycle and Signal Transduction * Viral Carcinogenesis * Environmental Carcinogenesis * Cancer Metastasis * Tumor Immunology and Immunotherapy * Technologies in Molecular Biology: Diagnostic Applications * Section III. Cancer Prevention and Control * Cancer Epidemiology * Evidence-Based Cancer Prevention Research: A Multidisciplinary Perspective on Cancer Prevention Trials * Screening * Genetic Screening and Counseling for High-Risk Populations * Behavior Modification * Section IV. Cancer Imaging * Central Nervous System Imaging * Chapter 28. Breast Imaging * Imaging of Thoracic Malignancies * Imaging of Gastrointestinal Stromal Tumor * Genitourinary Imaging * Musculoskeletal Imaging * PET * Section V. Solid Tumors * Central Nervous System Tumors * Eye, Orbit, and Adnexal Structures * Head and Neck Cancer * Lung * Therapy for Malignant Pleural Mesothelioma * Mediastinum * Esophageal Cancer * Stomach * Colon, Rectal and Anal Cancer Management * Adenocarcinoma and Other Small Intestinal Malignancies * Cancer of the Liver and Bile Ducts * An Evidence-Based Approach to the Management of Pancreatic Cancer * Renal Cell Cancer * Ureter, Bladder, Penis, and Urethra * Prostate Cancer * Testis Cancer * Cervix, Vulva, and Vagina * Gestational Trophoblastic Neoplasia * Ovarian Cancer * Uterine Malignancies * Evidence-Based Management of Breast Cancer * Thyroid and Parathyroid * Tumors of the Endocrine System * Sarcomas of Bone * Soft Tissue Sarcoma * Cutaneous Melanoma * Nonmelanoma Cutaneous Malignancies * Cancer of Unknown Primary Site * Solid Tumors of Childhood * Section VI. Hematologic Malignancies * Acute Myeloid Leukemia and the Myelodysplastic Syndromes * Acute Lymphoblastic Leukemia * Chronic Lymphocytic Leukemia and Related Chronic Leukemias * Chronic Myeloid Leukemia * An Evidence-Based Approach to the Management of Hodgkin’s Lymphoma * Non-Hodgkins Lymphomas * Plasma Cell Lymphomas * Section VII. Practice of Oncology Oncologic Emergencies * Superior Vena Cava Syndrome * Central Nervous System Emergencies * Metabolic Emergencies in Oncology * Surgical Emergencies * Acute Toxicities of Therapy * Oral Complications of Cancer Therapy Alopecia and Cutaneous Complications of Chemotherapy * Infectious Complications of Cancer Therapy * Acute Toxicities of Therapy: Pulmonary Complications * Cardiac Complications * Neurologic Complications of Therapy * Acute Toxicities of Therapy: Urologic Complications * Supportive Care * Management of Cancer Pain * Nausea and Vomiting in the Cancer Patient * Nutritional Support for the Cancer Patient * Paraneoplastic Syndromes * Malignant Effusions * Bone Marrow Dysfunction in the Cancer Patient (RMS) * Management of the Bone Marrow Transplant Patient * Management of Anxiety and Depression in Adult Cancer Patients: Toward an Evidence-Based Approach Reproductive Complications and Sexual Dysfunction in the Cancer Patient * The Care of the Terminal Patient * Care of Site-Specific Metastatic Disease * Metastatic Cancer to the Central Nervous System * Metastatic Cancer to Lung * Surgical and Regional Therapy for Liver Metastases * Metastatic Cancer to Bone * Care of Unique Subpopulations * Cancer in the Immunosuppressed Patient (RMS)* Cancer in the Older Population * Chemotherapy in Patients with Organ Dysfunction * Management of the Pregnant Cancer Patient * Section VIII. Cancer Survivorship * Survivorship Research: Past, Present and Future * Late Effects of Cancer Treatments * Medical and Psychosocial Issues in Childhood Cancer Survivors * Chapter 103. Medical and Psychosocial Issues in Hodgkin’s Disease Survivors * Medical and Psychosocial Issues in Testicular Cancer Survivors * Medical and Psychosocial Issues in Gynecological Cancer Survivors * Medical, Psychosocial, and Health-Related Quality of Life Issues in Breast Cancer Survivors * Medical and Psychosocial Issues in Prostate Cancer Survivors * Physical and Psychosocial Issues in Lung Cancer Survivors * Cancer Survivorship Issues in Colorectal Cancer * Medical and Psychosocial Issues in Transplant Survivors * Second Malignancies after Radiation Treatment and Chemotherapy for Primary Cancers * Psychosocial Rehabilitation in Cancer Care * Cancer Advocacy Do góry Hyperthermia In Cancer Treatment A Primer Baronzio, Gianfranco (Ed.) 2006, 125 illus., Hardcover ISBN: 0-387-33440-8 Due: September 2006 Price: 134,95 EUR + shipping 10,00 EUR NASZA CENA: 525,00 PLN* About this book Following an introductory overview, Hyperthermia In Cancer Treatment: A Primer comprehensively describes the biological reasons for associating hyperthermia with radiation and chemotherapy and the biological and clinical effects of hyperthermia on cancerous and normal tissues. The volume’s 20 chapters are arranged in three principal parts: physical and methodological studies, biologic principles, and clinical studies. Table of contents Hyperthermia, Physics, Vector Potential, Electromagnetic Heating: A Primer.- Thermometry: Clinical Aspects and Perspectives.- Physical Background and Technical Realizations of Hyperthermia.- Thermotherapy and Nanomedicine: Between Vision and Reality.- Influence of Tumor Microenvironment on Thermoresponse: Biologic and Clinical Implications.- Hyperthermia and Angiogenesis: Results and Perspectives.- Vascular Effects of Localized Hyperthermia.- On the Biochemical Basis of Tumour Damage by Hyperthermia.- Results of Hyperthermia Alone with Radiation Therapy and/or Chemotherapy.- Thermo-Chemo- Radiotherapy Association: Biological Rationale, Preliminary Observations on Its Use on Malignant Brain Tumors.- A Step Deep on Hyperthermia, Hypoxia and Chemotherapy Interactions.- Locoregional Hyperthermia.- Hyperthermia and Radiotherapy in the Management of Prostate Cancer.- Tumor Ablation Using Radiofrequency Energy: Technical Methods and Application on Liver Tumors.- Cytoreduction, Peritonectomy and Hyperthermic Antiblastic Peritoneal Perfusion for the Treatment of Peritoneal Carcinomatosis.- Hyperthermic Isolated Limb Perfusion.- Intracavitary Hyperthermic Perfusion.- Whole Body Hyperthermia at 43.5-44°C: Dreams or Reality?.- Extreme Whole-Body Hyperthermia with Water-Filtered Infrared-A Radiation.- Effects of Local and Whole Body Hyperthermia on Immunity.- Fever, Pyrogens and Cancer.- Future Perspectives of Interstitial and Perfusional Hyperthermia.- Index. Do góry New Trends in Cancer for the 21st Century Series: Advances in Experimental Medicine and Biology , Vol. 587 López-Guerrero, J.A.; Llombart-Bosch, A.; Felipo, V. (Eds.) 2006, XXIV, 396 p., 97 illus., Hardcover ISBN: 1-4020-4966-8 Due: September 2006 Price: approx. 115,00 EUR + shipping 10,00 EUR About this book It is difficult to imagine anyone who has not heard of cancer. This disease can affect families, friends or any one of us at any time in our lives. Every year nearly 3 million Europeans are diagnosed with cancer, leading to around 800,000 deaths per year. These deaths occur not only in aging populations, but also in children and adults who are in the most active period of their lives. This represents a tremendous problem that cannot be ignored by politicians or citizens. Fortunately, there is a constantly growing awareness that although cancer is a problem to be dealt with by clinicians, it should also be the concern of everyone. This volume contains the lectures held at the International Symposium on Cancer "New Trends in Cancer for the 21st Century". Fundamental researchers, politicians and representatives from patient coalitions share here their knowledge and interests as well as their concerns and experiences. Not only do these papers provide state-of-the-art information on cancer, they are also an opportunity to look at the problem from different points of view. It can be encouraging to realise that we are not alone in this fight. Table of contents 1. Prognostic and Therapeutic Targets in the Ewing’s Family of Tumors (ProTheTs), P. Picci, K. Scotlandi, M. Serra, and A. Rizzi.- 2. Targeted Therapies in Ewing’s Sarcoma K. Scotlandi.- 3. The CCN3 Protein and Cancer, B. Perbal.- 4. Ews-Fli1 in Ewing’s Sarcoma – Real Targets and Collateral Damage, J. Ban, C. Siligan, M. Kreppel, D. Aryee and H. Kovar.- 5. Molecular Karyotyping in Sarcoma Diagnostics and Research, H. Vauhkonen, S. Savola, S. Kaur, M. L. Larramendy and S. Knuutila.- 6. Tubafrost: European Virtual Tumor Tissue Banking, P. H. J. Riegman, M. H. A. Oomen, W. N. M. Dinjens, J. W. Oosterhuis, K. H. Lam, A. Spatz, C. Ratcliffe, K. Knox, R. Mager, D. Kerr, F. Pezzella, B. van Damme, M. van de Vijver, H. van Boven, M. M. Morente, S. Alonso, D. Kerjaschki, J. Pammer, J. A. Lopez-Guerrero, A. Llombart Bosch, A. Carbone, A. Gloghini, I. Teodorovic, M. Isabelle, A. Passioukov, S. Lejeune, P. Therasse and E-B. van Veen.- 7. Virtual Microscopy in Virtual Tumor Banking, M. Isabelle, I. Teodorovic, J. W. Oosterhuis, P. H. J. Riegman and the TuBaFrost Consortium.- 8. Harmonizing Cancer Control in Europe, U. Ringborg.- 9. The Diagnosis of Cancer: "From H&E to Molecular Diagnosis and Back", J. Costa.- 10. From Morphological to Molecular Diagnosis of Soft Tissue Tumors, M. Miettinen.- 11. Prediction of Response to Neoadjuvant Chemotherapy in Carcinomas of the Upper Gastrointestinal Tract H. Höfler, R. Langer, K. Ott and G. Keller.- 12. Integrating the Diagnosis of Childhood Malignancies, D. López-Terrada.- 13. Preclinical Models for Cell Cycle-Targeted Therapies, M. Malumbres.- 14. WWOX, a Chromosomal Fragile Site Gene and its Role in Cancer, Ramos D. and Aldaz C. M.- 15. From Genome to Proteome in Tumor Profiling, J. K. Habermann, U. J. Roblick, M. Upender, T. Ried and G. Auer.- 16. Effect of Hypoxia on the Tumor Phenotype: the Neuroblastoma and Breast Cancer Models, L. Holmquist, T. Löfstedt and S. Pahlman.- 17. Methylation Patterns and Chemosensitivity in NSCLC, J. L. Ramirez, M. F. Salazar, J. Gupta, J. M. Sánchez, M. Tarón, M. Sánchez-Ronco, Vicente Alberola and R. de las Penas.- 18. Pharmacogenomics and Colorectal Cancer, H. J. Lenz.- 19. Development of Pharmacogenomic Predictors for Preoperative Chemotherapy of Breast Cancer, L. Pusztai.- 20. Vascular Endothelial Growth Factor Inhibitors in Colon Cancer, E. Díaz-Rubio.- 21. Molecular Imaging of Cancer Using PET and SPECT, A. Kjar, B. Celda, D. Monleón, M. C. Martínez-Bisbal, V. Esteve, B. Martínez-Granados, E. Pinero, R. Ferrer, J. Piquer, L. Martí-Bonmatí and J. Cervera.- 23. From Linac to Tomotherapy: New Possibilities for Cure? G. Storme, D. Verellen, G. Soete, N. Linthout, J. Van de Steene, M. Voordeckers, V. Vinh-Hung, K. Tournel, and D. Van den Berge.- 24. Targeting mTOR for Cancer Treatment, B. Rubio-Viqueira and M. Hidalgo.- 25. Dual/Pan-Her Tyrosine Kinase Inhibitors (TKI): Focus in Breast Cancer, J. Albanell.- 26. Anti-Tumor Associated Antigens IGGS. Dual Positive and Negative Potential Effects For Cancer Therapy, E. Barberá-Guillem and J. W. Sampsel.- 27. Synergistic Molecular Mechanisms in Hormone Sensitive Breast Cancer, A. Llombart Cussac.- Contributors.- Index Do góry Breast Cancer Management and Molecular Medicine: Towards Tailored Approaches Piccart, M.J.; Wood, M.D., W.C.; Hung, M.-C.; Solin, L.J.; Cardoso, F. (Eds.) 2006, LV, 1014 p., 140 illus., Hardcover ISBN: 3-540-28265-3 Due: September 2006 Price: 159,95 EUR + shipping 10,00 EUR NASZA CENA: 615,00 PLN* About this book Tailoring treatment for individual breast cancers is no longer a dream and is now the main goal for current research. This book gives an overview of the most recent techniques, agents and approaches for breast cancer and the individualization of treatment. Particular attention is given to organ-specific tailored approaches, specific populations, patients’ preferences and rehabilitation. Contributions from experts focus on the biomedical research behind the transfer of molecular biology knowledge into the clinical management of patients. This has led to increased survival as well as improved quality of life. The book gives an overview of the latest achievements in breast cancer and their use in clinical practice. Table of contents Overview.- Staging and Imaging.- Genetic and High Risk Syndromes.- DCIS.- StageI/II Breast Cancer Surgery.- StageI/II Breast Cancer-Radiotherapy.- StageI/II Breast Cancer-Systemic therapy.- Locally-advanced breast cancer.- Organ specific tailored approaches.- Genomics and Proteomics.- Biolgoical therapies.- Basic science-clinical applications.- Special Problems Do góry Breast Cancer Third Edition Edited By Orlando Silva, MD, JD, FACP, FCLM, Director of Breast Cancer Education, Assistant Professor of Clinical Medicine, Leonard M. Miller School of Medicine, University of Miami, Miami, FL Stefano Zurrida, MD, Current Secretary to the Minister of Health of Italy, Istituto Europeo di Oncologia, Direzione Scientifica, Milan, Italy Paperback, ISBN: 0-7020-2744-8 672 pages, publication date: 2006 Imprint: SAUNDERS Description Totally updated, including data from ASCO 2005, and revised to include a synopsis of the current wealth of literature available, this best-selling text still retains its original purpose which is to provide an indispensable compendium of all the current information and studies on breast cancer. Allowing oncologists, primary care physicians, medical students and nurses to base their practice on the current evidence found in the literature, this book is essential for ensuring that practice is evidence based. Contents 1 BENIGN BREAST DISEASE BREAST CARCINOMA 2 HISTORY OF BREAST CANCER 3 EPIDEMIOLOGY 4 RISK FACTORS 5 SCREENING 6 IMAGING STUDIES 7 EVALUATION OF A PALPABLE BREAST MASS AND NIPPLE DISCHARGE 8 BREAST PATHOLOGY 9 STAGING 10 PROGNOSTIC FACTORS NON-INVASIVE CANCER: CARCINOMA IN SITU 11 DCIS (Ductal Carcinoma in Situ) 12 LCIS (Lobular Carcinoma In Situ) 13 ACCELERATED PARTIAL BREAST IRRADIATION (APBI) INVASIVE CANCER 14 SURGICAL TREATMENT 15 POST-MASTECTOMY RADIOTHERAPY 16 AXILLARY LYMPH NODE DISSECTION (ALND) 17 AXILLARY LYMPH NODE IRRADIATION 18 BREAST RECONSTRUCTION AFTER MASTECTOMY 19 STAGE III DISEASE 20 PRIMARY CHEMOTHERAPY 21 ADJUVANT Chemo THERAPY IN PRE- AND POST-MENOPAUSAL 22 ADJUVANT ENDOCRINE THERAPY IN PRE- AND POST-MENOPAUSAL 23 LOCAL BREAST RECURRENCE 24 METASTATIC BREAST CANCER PRESENTATIONS AND MANAGEMENT 25 ENDOCRINE THERAPY FOR METASTATIC BREAST CANCER 26 STANDARD CHEMOTHERAPY FOR METASTATIC BREAST CANCER 27 BREAST CANCER AND THE ELDERLY 28 SIDE EFFECTS OF CHEMOTHERAPY 29 INVESTIGATIONAL AGENTS 30 HIGH-DOSE THERAPY 31 PSYCHOSOCIAL ISSUES IN BREAST CANCER 32 BREAST CANCER AND DEPRESSION 33 FOLLOWING BREAST CANCER PATIENTS 34 MENOPAUSAL SYMPTOMS AND THEIR MANAGEMENT UNUSUAL PRESENTATIONS 35 PAGET DISEASE 36 BREAST CANCER AND PREGNANCY 37 PHYLLODES TUMOR 38 OCCULT BREAST CANCER PRESENTING AS A SOLITARY AXILLARY MASS 39 PARANEOPLASTIC SYNDROMES IN BREAST CANCER 40 MALE BREAST 41 CHEMOPREVENTION 42 CARE OF THE DYING PATIENT 43 ISSUES IN BREAST CANCER LIABILITY A1 National Breast Cancer Support Organisations A2 Breast Cancer Local Support Groups in the USA A3 CHARGES RELATED TO BREAST CANCER TREATMENT IN THE U.S.A. & EUROPE Do góry Prognostic Factors in Cancer, 3rd Edition Mary K. Gospodarowicz, Brian O'Sullivan, Leslie H. Sobin ISBN: 0-470-03801-2 Paperback 353 pages August 2006 Price: 46,50 GBP + shipping 5,00 GBP Description Prognostic Factors in Cancer, Third Edition examines the prognostic factors associated with each cancer site and provides insight into potential treatments and therapies. The text is an extension of the International Union Against Cancer's (UICC) seminal work, the TNM Classification of Malignant Tumours, and integrates the current focus on prognostics in cancer. This Third Edition reflects the advances in cancer diagnosis and treatment planning made in recent years. The first part of the book offers a complete update on the science of cancer prognosis while the second part contains site-specific chapters that provide evidence-based guidelines for treatment. Each clinical chapter summarizes the significance of the great variety of tumour-related, patient-related, and environment-related factors that play a role in the prognosis of cancer, all backed with a grid for quick reference. Prognostic Factors in Cancer, Third Edition is an invaluable resource for all oncologists and cancer researchers. The title is also of interest for other professionals such as pathologists and epidemiologists. Table of Contents Preface. Acknowledgements. Contributors. PART A. PRINCIPLES OF PROGNOSTIC FACTORS. 1. The Importance of Prognosis in Cancer Medicine (William Mackillop). 2. Principles of Documenting Prognosis and Prognostic Factors in Cancewr (Mary Gospodarowicz, Brian O’Sullivan and Eng-Siew Koh). 3. Studies Investigating Prognostic Factors: Conduct and Evaluation (Douglas Altman). 4. Prognostic Factors in Population Based Cancer Control (Patti Groome). 5. Prognostic Factors in Terminal Cancer (Paul Glare). 6. Incorporating Molecular Oncology into Prognosis (Geoffrey Liu, Wei Zhou, Zhaoxi Wang and Howard McLeod). PART B. PROGNOSTIC FACTORS IN SPECIFIC CANCERS. SECTION 1. HEAD AND NECK TUMORS (BRIAN O’SULLIVAN). 7. Oral Cavity, Pharynx, and Larynx Cancer (Jean Bourhis). 8. Paranasal Sinus Cancer (John Waldron). 9. Nasopharyngeal Cancer (Joseph wee and Eng Huat Tan). 10. Salivary Gland Cancer (Adam Garden). 11. Thyroid Cancer (James Brierley and Sylvia Asa). SECTION 2. DIGESTIVE SYSTEM TUMORS (FREDERICK GREENE AND CHRISTIAN WITTEKIND). 12. Esophagus Cancer (Hubert J. Stein). 13. Gastric Cancer (Burkhand von Rahden). 14. Colorectal Cancer (JHJM van Krieken and Cornelis van de Velde). 15. Anal cancer (Bernard Cummings). 16. Hepatocellular Cancer (Philip Johnson and Daniel Palmer). 17. Extrahepatic Biliary Tract and the Ampulla of Vater Cancers (Christian Wittekind). 18. Pancreas Cancer (John Neoptolemos and Paula Ghaneh). SECTION 3. LUNG AND PLEURAL TUMORS (CHRISTIAN WITTEKIND AND PATTI GROOME). 19. Lung Cancer (Michael Brundage and William Mackillop). 20. Malignant Pleural Mesothelioma (Richard Battafarano and N. K. Veeramachaneni). 21. Malignant Thymoma (Andrea Bezjak and David G. Payne). SECTION 4. TUMORS OF BONE AND SOFT TISSUES (BRIAN O’SULLIAN). 22. Osteosarcoma (Henrik C. F. Bauer). 23. Soft Tissue Sarcoma (Charles Catton and Brian O’Sullivan). 24. Gastrointestinal Stromal Tumors (Jaap Verweij and Stefan Sleijfer). SECTION 5. SKIN TUMORS (LESLIE SOBIN). 25. Skin Cancer (Michael Poulsen). 26. Cutaneous Malignant Melanoma (Peter J. Heenan and Trevor Beer). SECTION 6. BREAST CANCER (FREDERICK GREENE). 27. Breast Cancer (Daniel F. Hayes). SECTION 7. GYNECOLOGIC CANCERS (MARY GOSPODAROWICZ). 28. Vulvar Cancer (Neville Hacker and Donald Marsden). 29. Uterine Cervix Cancer (Jan Hauspy, Ian Harley and Anthony Fyles). 30. Ovarian and Fallopian TubeCancer (Sergio Pecorelli, Brunella Pasinetti, Giancarlo, Lucia Zigliani and Franco E. Odicino). 31. Endometrial Cancer (Michael Milosevi and Fernanda Herrera). 32. Gestational Trophoblastic Disease (Hextan Ngan, Karen K.L. Chan and Kevin F. Tan). SECTION 8. UROLOGICAL TUMORS (MARY GOSPODAROWICZ). 33. Penile Cancer (Simon Horenblas and Juanita Crook). 34. Prostate cancer (Louis Denis and Padraig Warde). 35. Germ Cell Tests Tumors (Hans-Joachim Schmoll and Peter Chung). 36. Renal Cell Cancer (Christophe Ghysel, Steven Joniau and Heindrik Van Poppel). 37. Bladder cancer (Adrian van der Meijden and Richard Sylvester). SECTION 9. OPHTHALMIC TUMORS (LES SOBIN). 38. Uveal Melanoma Tumors (Jerry Shields and Carol Shields). 39. Retinoblastoma (Vikas Khetan, Helen S. L. Chan, Lisa Wang and Brenda L. Gallie). SECTION 10. HEMATOLOGIC MALIGNANCIES (MARY GOSPODAROWICZ). 40. Hodgkin Lymphoma (Lena Specht). 41. Non-Hodgkin Lymphoma (M. Gospodarowicz, M. Crump and E. Zucca). 42. Leukemia (Mark Minden, P. Disperati, F. Suarez-Saiz and H. Khoury). 43. Multiple Myeloma (Jesus San Miguel and Norma C. Guti43. Multiple Myeloma (Jesus San Miguel and Norma C. Gutierrez). SECTION 11. BRAIN TUMORS (BRIAN O’SULLIVAN). 44. Gliomas (Michael Brada, Paul Kleihues, Guiseppe Minniti and Hiroko Ohgaki). SECTION 12. PEDIATRIC TUMORS (FREDERICK GREENE). 45. Pediatric Cancers (Eric Bouffet, David C. Hodgson and Eng-Siew Koh). Epilogue. Glossary. Index. Do góry Infections Causing Human Cancer Harald zur Hausen ISBN: 3-527-31056-8 Hardcover 531 pages September 2006 Price: 105,00 GBP + shipping 5,00 GBP NASZA CENA: 592,00 PLN* Description Infections must be thought as one of the most important, if not the most important, risk factors for cancer development in humans. Approximately 15-20% of all cases of cancer around the world are caused by viruses. The establishment of a causal relationship between the presence of specific infective agents and certain types of human cancer represents a key step in the development of novel therapeutic and preventive strategies. In this book, Professor zur Hausen provides a thorough and comprehensive overview on carcinogenic infective agents -- viruses, bacteria, parasites and protozoons -- as well as their corresponding transforming capacities and mechanisms. The result is an invaluable and instructive reference for all oncologists, microbiologists and molecular biologists working in the area of infections and cancer. The author was among the first scientists to reveal the cervical cancer-inducing mechanisms of human papilloma viruses and isolated HPV16 and HPV18, and, as early as 1976, published the hypothesis that wart viruses play a role in the development of this type of cancer. Table of Contents HISTORICAL REVIEW The Early Period (1898-1911) Frustration and Successes (1912-1950) The Period from 1950 to 1965 A First Human Tumor Virus? The Difficult 1970s The Re-emergence of a Concept THE QUEST FOR CAUSALITY Infectious Agents as Direct Carcinogens Infectious Agents as Indirect Carcinogens TUMORS LINKED TO INFECTIONS - SOME GENERAL ASPECTS Tumor Types Linked to Infections Global Contributions of Infections to Human Cancer Host Interactions with Potentially Carcinogenic Infections HERPESVIRUSES AND ONCOGENESIS Alphaherpesviridae Betaherpesviridae Gammaherpesviridae PAPILLOMAVIRUSES - A MAJOR CAUSE OF HUMAN CANCERS Introduction Concept of Viral Interfering Cascades Cancers Linked to HPV Infections Role of Co-factors Preventive Vaccination Therapeutic Vaccination Therapy HEPADNAVIRUS FAMILY Hepatitis B Virus Animal Hepadnaviruses FLAVIVIRUS FAMILY Hepatitis C Virus RETROVIRUS FAMILY Human T-lymphotropic Retroviruses 1 (HTLV-1) Human T-lymphotropic Retroviruses 2 (HTLV-2) Human Endogenous Retroviruses Gibbon Ape Leukaemia Virus and Simian Sarcoma Virus OTHER VIRUS INFECTIONS POSSIBLY INVOLVED IN HUMAN CANCERS Polyomaviruses (JC, BK and SV40) HELICOBACTER, CHRONIC INFLAMMATION AND CANCER Discovery, Taxonomy and Genomics Life Cycle, Specificity, and Virulence Determinants in Cancer Development Prevention of H. Pylori Induced Cancer Animal Models Virulence Determinants of Enterohepatic Helicobacter Spp Enterohepatic Helicobacter Spp. - Are they Cocarcinogens? PARASITES AND HUMAN CANCER Schistosomiasis Infection with Liver Flukes (Opisthorchis Viverrini, O. Felineus, Clonorchis Sinensis) CANCERS WITH A POSSIBLE INFECTIOUS ETIOLOGY Leukemias and Lymphomas Human Breast Cancer Other Human Cancers Possibly Linked to Infectious Events Do góry